The article concerns the problems of functioning the publishing and printing industry in Siberia and the Far East at the early XXI century: peculiarities of its infrastructure forming, entering the country’s printing services market, the place of a region in it. The paper objective is to represent the modern publishing and printing industry in Siberia and the Far East, its structural components, and determine the likely directions for further development of the regional market to printing product and service producers. The article reveals that, at the region territory, there are printing enterprises of various forms of ownership, production scale, printing technologies used, producing practically all types of publishing products of a wide range – from text editions to special ones. The leaders of the modern printing industry in the region are still the largest regional/area printing houses/media holdings - the flagships of the printing industry of certain territories in terms of provided products and services. At the same time, small printing enterprises start to play an increasing role, responding more flexibly and quickly to changes in consumer demand, changes and challenges of the printing services market. Their number in the region is quite large. The basis of small printing enterprises are district/city printing houses, print shops, advertising agencies, mini-printing houses, publishing centers. One can observe the continuation of the activity diversification of the largest printing houses in the region and the general digitalization of the activities of enterprises in the industry.