Н. М. Пржевальский | Библиотека ELiS

On the 95th anniversary of Professor Igor I. Grandberg (1930–2011)

Submitted by Гость (not verified) on Wed, 02/04/2026 - 22:38

This article examines the scientific and pedagogical activities of Igor I. Grandberg, a prominent Soviet and Russian scientist in the field of organic chemistry, Honored Scientist of the Russian Federation, Doctor of Chemical Sciences, and Professor. A brief biography of the scientist is presented, showcasing his contribution to both national and global science. I. I. Grandberg’s scientific interests were focused on the development of novel synthetic methods and the study of the chemical and biological properties of heterocyclic compounds.

Cytotoxicity of pyranopyridones with tryptamine fragment

Submitted by Гость (not verified) on Tue, 07/09/2024 - 16:45

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New derivatives of pyrano[3,2-c]pyridones III 5, 10, 15, 18 were synthesised by threecomponent reaction of pyridonotryptamines I, aromatic aldehydes II and malononitril. Pyridonotryptamines I were synthesised by reaction of tryptamines (these compounds were obtained by Grandberg reaction of arylhydrazines with γ-halogencarbonyl compounds) with 4-hydroxy- 6-methyl-2H-pyran- 2-on. The aromatic aldehydes II 1, 5, 6, 9 are commercially available compounds.

Professor Ryurik A. Khmelnitsky (on the 90th anniversary of the scientist)

Submitted by Гость (not verified) on Tue, 07/09/2024 - 16:45

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