Lateral roots play an important role in the formation of an extensive rootage, and therefore determine plant’s potential in search and consumption of water and mineral nutrients and its mechanical attachment to the soil. In contrast to initiation, the development of lateral roots after their emergence from the main root has relatively recently become a separate object of scientific research. Based on the length, an angle relative to the gravity vector, and the number of cells in the columella, six stages of lateral root development have been distinguished. As in the case of the main root, the plant hormones, auxin and cytokinin, play a leading role in lateral root homeostasis. However, at different development stages, the responses of the lateral roots to auxin, cytokinin and abscisic acid differ significantly from the responses of the main root and have a significant influence on the rootage. Differences in the organization of endogenous regulation of the main and lateral roots are clearly manifested in the individual response of the main root and lateral roots to the availability of certain elements of mineral nutrition and salt stress. This review discusses relevant data on the growth rate, orientation, and mechanisms regulating growth and development of lateral roots of the Arabidopsis thaliana model plant.