The article presents data on the feasibility of using the natural organomineral phytomodulator “Beliy Zhemchug Antifreeze” (NOP BZh Antifreeze) to increase the resistance of a lowwinter-hardy blackberry crop to low freezing temperatures. The objects of the study were erect and semi-erect varieties of blackberries – “Ouachita”, “Chester”, “Black Magic”, “Black Gem”, “Loch Tay”. The experiment was carried out in the Moscow region, Dmitrovsky district, in a private berry nursery. The seedlings were grown in 10-litre containers for two years. There were three variants in the experiment: 1) spunbond with a density of 90 g / m2 was used as a winter shelter together with the application of the phytomodulator NOC BZh Antifreeze for protection against low-temperature stress; 2) treatment of plants with NOP BZh Antifreeze without winter shelter; 3) control plants were without shelter and without treatment. Comparing the samples using the Mann-Whitney test confirmed the hypothesis of reliable differences between the experimental variants. With the complex application of protective measures (treatment with the phytomodulator and shelter), the erect varieties “Black Magic” and “Black Gem” proved to be the most resistant to freezing temperatures, their shoots were not damaged (0 points.). The least resistant semi-erect variety was “Ouachita”, in the control variant (without shelter and without treatment with phytomodulator), significant shoot damage was observed (3 points.), while with complex protective measures winter damage was 1 point. The data obtained made it possible to recommend the use in nurseries of a combination of protective measures (treatment with the phytomodulator and shelter) against low-temperature stress – sheltering blackberry shoots with spunbond with the use of NOP BZh Antifreeze.