The article is devoted to the study of the documentary heritage, its role in the socio-economic development of the region. The author highlighted the basic requirements of regulations in preserving the documentary heritage in the region. The purpose of the article is to show the library and university capabilities in implementing tasks to preserve and promote cultural heritage for the further development of the territory on the basis of the results of the conducted research. Using the example of the Kemerovo region (Kuzbass), the main parameters of the documentary heritage usage for socio-economic development of the region are determined: ensuring preservation of the documentary heritage; providing access to information; information support for all aspects of regional development; creating digital content of memory institutions (libraries, museums, archives); promoting the documentary heritage; putting into scientific circulation new components of the documentary heritage; research activities; integration of memory institutions for to preserve cultural heritage. The article presents the description of the digital documentary heritage of Kuzbass in the central library (V. D. Fedorov State Scientific Library of Kuzbass). The main types of work of the Kemerovo State Institute of Culture (KemSIC) in preserving and promoting the cultural heritage of Kuzbass are outlined. The article also considers the integration of the activities of the central library with the culture university as one of the key factors in increasing the efficiency of work in this direction. It is emphasized that cooperation between libraries and other institutions and organizations, including authorities and local self-government allows to work out and implement joint projects aimed at developing the region and increasing its level of sustainability. It is noted that the central libraries of the constituent entities of the Russian Federation and the Universities of Culture are key participants in the preservation and development of the cultural heritage of the region. The main conclusion of the study: close integration of the library and the university makes it possible to solve complex problems of preserving and promoting the documentary heritage of the region.