The purpose of our research was to analyze the influence of variety properties, seeding rates and methods of crop care on the level of weediness, productivity and quality of soybeans on row-sown crops. It was done by determining the number of weeds in an agrophytocenosis, productivity level, protein and oil content in soybeans. The author has proved a possibility of soybean cultivation without applying herbicides, using drilling sowing with the lowest yield losses caused by weediness. It has been established that varieties with larger foliaceous area compete with weeds in the best way. Increasing the soybean seeding rate forms a denser agrophytocenosis. This agrophytocenosis is more resistant to weeds. One pre-emergence and two post-emergence harrowing operations decrease the number of weeds by 76%. Varieties with longer vegetation period feature higher soybean productivity than precocious varieties. Optimal seeding rate for precocious variety Romantyka is 800 thousand/ha and an optimal seeding rate for precocious variety Ustya is 900 thousand/ha. The most favourable conditions for the growth and development of plants under the row sowing method were provided with a mechanical method of crop care. Weediness of crops negatively influence the soybean quality. A correlation dependence between protein and oil content has been established. Increasing the protein content results in decreased oil content in soybeans and vice-versa. Increasing the seeding rate leads to increased protein and decreased oil content.