The implementation of the National Security Strategy imposes special requirements on the agricultural sector of the economy as the basis for ensuring the country’s food security. A comprehensive solution to the tasks set out in the Food Security Doctrine of the Russian Federation, the State Program for the Development of Agriculture and Regulation of Agricultural Products, Raw Materials and Food markets is impossible without modernizing the drivers of development of sectoral economic growth. Under the conditions of sanctions and a pandemic, the Russian agricultural sector of the economy maintains positive growth dynamics, investment attractiveness, and the role of labor efficiency increases. The development of agribusiness, the growth of expenses for organizing a business, the slowdown in production by households require appropriate regulatory and support measures; investments in the agricultural sector of the economy should be targeted. Problem Statement. Modern conditions for ensuring food security have changed the drivers of economic growth in the agricultural sector of Russia. Results. The interaction and interdependence of the drivers of the development of the agricultural sector considered in the paper will make it possible to realize the directions of economic growth in Russia. Conclusions. Drivers of economic growth in the agricultural sector of Russia in 2022–2023 are creation of new jobs, human development, labor productivity growth, creation of comfortable working conditions, high-level processing, reducing output of low value-added products, digitalization.