The authors made assessment of agroclimatic resources in KhMAO-Yugra based on observed meteorological data obtained from 53 meteorological posts over the period of2005-2016. It was found that the climate change on the territory of KhMAO has resulted in an increase of200°C in the sum of active temperatures (above the base growth that equals 10°C) over the past decade. These changes are caused by the prolonged growing season by 13-15 days. The average temperature of the hottest month has not been changed. The longer vegetation period can be mainly due to a longer climatic autumn that increased by an average of 9 days. The sum of negative temperatures in the cold season over the past decade has increased by 200-400°C, while maintaining the height of the snow cover. This fact made the rest period significantly more favorable for the over-wintering of perennial plants. There is a trend towards more even distribution of the precipitation amount between the warm and cold seasons. However, there remains excessive moisture during the growing season characterized by semiarid spring and the steady growth of hydration dynamics towards the end of the growing season. Based on the analysis made, the authors performed agroclimatic zoning: determined and identified the boundaries of the four agro-climatic areas of the district; provided detailed description of their agro-climatic resources; and evaluated the bioclimatic potential of the territory of the Khanty-Mansi Autonomous District and its agro-climatic regions. It is shown that due to the regionally available agroclimatic resources it is economically feasible to develop dairy and dairy-meat cattle breeding, combined with the cultivation of crops zoned for the territory of Western Siberia.