In the article the information on a systematic review as a form of analytical production is collected, analyzed and systematized. Characteristics of its main specific features and common ones with that of an analytical review are given, its short history is described. There is an original definition of a systematic review as an analytical product, with a volume of a large scientific article prepared on the basis of the results of a special scientific study, carried out according to special methods and designed to make the right clinical or social decision. The method of its preparing consisting of seven stages is described in detail, and the role of the library staff in each of them is defined. All presented data prove that a library employee can not only act as an organizer, but also as a member of a research group for preparing up-todate systematic reviews.